Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429633 | 0.71 | CA1 (0.71) | APPCA1CA2CA7CA9 | |
| SCHEMBL301996 | 0.71 | CA1 (0.71) | APPCA1CA2CA7CA9 | |
| SCHEMBL29788337 | 0.71 | CA1 (0.71) | APPCA1CA2CA7CA9 | |
| SCHEMBL29740506 | 0.69 | CA1 (0.67) | APPCA1CA2CA7CA9 | |
| SCHEMBL30599266 | 0.69 | CA1 (0.67) | APPCA1CA2CA7CA9 | |
| SCHEMBL3643541 | 0.69 | CA1 (0.67) | APPCA1CA2CA7CA9 | |
| SCHEMBL11099503 | 0.69 | CA1 (0.67) | APPCA1CA2CA7CA9 | |
| SCHEMBL27564617 | 0.68 | DPP4 (0.46) | — | |
| SCHEMBL28025956 | 0.67 | PTGS2 (0.49) | APPCA1CA2CA7CA9 | |
| SCHEMBL8592244 | 0.65 | CA1 (0.60) | APPCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675300-B2 | Group 3 metal compounds and use thereof in the treatment of solid tumors | Università degli Studi di Salerno (IT) | 2020-06-09 | — | — | US | claimed |
| EP-3452490-B1 | GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS | UNIV DEGLI STUDI DI SALERNO (IT) | 2020-05-13 | — | — | EP | claimed |
| US-20190240254-A1 | Group 3 Metal Compounds and Use Thereof in the Treatment of Solid Tumors | Università degli Studi di Salerno (IT) | 2019-08-08 | — | — | US | claimed |
| EP-3452490-A1 | GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS | Universitá Degli Studi Di Salerno (IT) | 2019-03-13 | — | — | EP | claimed |
| WO-2017191607-A1 | GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS | Università degli Studi di Salerno (IT) | 2017-11-09 | — | — | WO | claimed |
| EP-3452490-A1 | GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS | Universitá Degli Studi Di Salerno (IT) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017191607-A1 | GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS | Università degli Studi di Salerno (IT) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240254-A1 | Group 3 Metal Compounds and Use Thereof in the Treatment of Solid Tumors | CA4, CA13, CA14 | APP 4551/4885CA1 59/4885CA2 46/4885 |
| US-10675300-B2 | Group 3 metal compounds and use thereof in the treatment of solid tumors | CA4, CA13, CA14 | APP 4551/4885CA1 59/4885CA2 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.