Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168698 | 0.84 | PTPN11 (0.54) | PTPN11CA1CA2CA12CA7 | |
| SCHEMBL19513816 | 0.83 | PTPN11 (0.51) | PTPN11CYP19A1CYP11B1CYP11B2LCK | |
| SCHEMBL498052 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6135654 | 0.81 | MAPT (0.50) | PTPN11CA1CA2CA12CA7 | |
| SCHEMBL6132177 | 0.80 | PTPN11 (0.50) | PTPN11CA1CA2CA12CA7 | |
| SCHEMBL29365729 | 0.79 | PTPN11 (0.68) | PTPN11CYP19A1CYP11B1CYP11B2LCK | |
| SCHEMBL1914269 | 0.79 | CYP1A1 (0.38) | CYP11B1CYP11B2PLAU | |
| SCHEMBL69025 | 0.79 | PTPN11 (0.68) | PTPN11CYP19A1CYP11B1CYP11B2LCK | |
| SCHEMBL5566033 | 0.78 | PLAU (0.64) | PTPN11CYP19A1CYP11B1CYP11B2LCK | |
| SCHEMBL19712252 | 0.78 | KDM4E (0.46) | PTPN11CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |