Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829005 | 0.91 | KDM4E (0.63) | KDM4EALDH1A1ALOX12DEGS1NPC1 | |
| SCHEMBL21446855 | 0.88 | KDM4E (0.77) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL19554308 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL22213622 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL22213559 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL7041709 | 0.81 | PLAU (0.52) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL7038894 | 0.80 | PLAU (0.56) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL7033003 | 0.80 | PLAU (0.59) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL19554343 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1ALOX12NPC1RAB9A | |
| SCHEMBL7949189 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1ALOX12NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |