Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554207 | 0.91 | RAB9A (0.52) | KDM4EALDH1A1NR1H4GAANPC1 | |
| SCHEMBL19554145 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL21446855 | 0.80 | KDM4E (0.77) | KDM4EALDH1A1ALOX12NR1H4GAA | |
| SCHEMBL19554242 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1ALOX12NR1H4GAA | |
| SCHEMBL4829005 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1ALOX12NR1H4GAA | |
| SCHEMBL22213622 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1ALOX12NR1H4NPC1 | |
| SCHEMBL22213559 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1ALOX12NR1H4GAA | |
| SCHEMBL19554221 | 0.74 | KMT2A (0.64) | KDM4EALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL19554308 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1ALOX12NR1H4GAA | |
| SCHEMBL19554355 | 0.74 | DHODH (0.56) | KDM4EALDH1A1NR1H4GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |