Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16528370 | 0.94 | KDM4E (0.46) | CFTRKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL23040878 | 0.84 | CFTR (0.68) | CFTRKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL16529387 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL16528915 | 0.79 | KDM4E (0.45) | CFTRKDM4EALDH1A1HSD17B10IDO1 | |
| SCHEMBL29417318 | 0.79 | CFTR (0.45) | CFTRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23040875 | 0.79 | CFTR (0.45) | CFTRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16528088 | 0.78 | KDM4E (0.44) | CFTRKDM4EALDH1A1HSD17B10IDO1 | |
| SCHEMBL9573792 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL16637057 | 0.78 | CFTR (0.64) | CFTRKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL7471868 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |