Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554300 | 0.88 | MAPT (0.56) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554093 | 0.86 | SMN1; SMN2 (0.62) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554221 | 0.86 | KMT2A (0.64) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554283 | 0.86 | KDM4E (0.60) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554243 | 0.85 | KMT2A (0.57) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554329 | 0.83 | MAPT (0.59) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554109 | 0.82 | MEN1 (0.53) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554137 | 0.82 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554179 | 0.80 | MEN1 (0.52) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL19554290 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |