Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749138 | 0.88 | PTPN11 (0.54) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL11467556 | 0.84 | AKR1C3 (0.49) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL11469677 | 0.84 | TDP1 (0.52) | PTPN11LCKPTGS2AKR1C3AKR1C2 | |
| SCHEMBL11471011 | 0.84 | AKR1C3 (0.65) | PTPN11LCKPTGS2AKR1C3AKR1C2 | |
| SCHEMBL29365729 | 0.84 | PTPN11 (0.68) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL69025 | 0.84 | PTPN11 (0.68) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL472487 | 0.82 | CA1 (0.57) | CA1CA2CA12CA7XDH | |
| SCHEMBL8732524 | 0.82 | PTPN11 (0.66) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL19554295 | 0.80 | PTPN11 (0.53) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL9979782 | 0.80 | PTPN11 (0.64) | PTPN11LCKCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |