SCHEMBL195552

SCHEMBL195552

CC(=O)Oc1ccc(C)cc1C(C)=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
CFD P00746 2/20 0.53
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LMNA P02545 2/20 0.48
ABCB1 P08183 1/20 0.48
KDM4E B2RXH2 3/20 0.47
TSHR P16473 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
HPGD P15428 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1317371 0.87 CFD (0.71) KMT2ACFDALDH1A1RAB9ANPC1
SCHEMBL30482833 0.84 SRC (0.58) KMT2AALDH1A1SMN1; SMN2LMNAABCB1
SCHEMBL1210111 0.84 SRC (0.58) KMT2AALDH1A1SMN1; SMN2LMNAABCB1
SCHEMBL12773409 0.82 KMT2A (0.55) KMT2AALDH1A1LMNAABCB1DDB1
SCHEMBL8350024 0.82 TSHR (0.60) CFDALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL6301456 0.81 TSHR (0.49) KMT2ACFDALDH1A1RAB9ANPC1
SCHEMBL15759757 0.81 KMT2A (0.54) KMT2AABCB1DDB1CRBNMEN1
SCHEMBL18928202 0.81 MAPT (0.59) KMT2ACFDALDH1A1RAB9ANPC1
SCHEMBL22950969 0.81 KDM4E (0.61) KMT2ACFDALDH1A1RAB9ANPC1
SCHEMBL789388 0.81 PTGDR2 (0.63) CFDALDH1A1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070263060-A1 Hybrid Energy Curable Solvent-Based Liquid Printing Inks SUN CHEMICAL CORPORATION 2007-11-15 US claimed
WO-2005071027-A1 HYBRID ENERGY CURABLE SOLVENT-BASED LIQUID PRINTING INKS SUN CHEMICAL CORPORATION (US) 2005-08-04 WO claimed
US-20020016226-A1 UV curable coating for golf balls LORD CORPORATION 2002-02-07 US claimed
WO-2001094452-A2 UV CURABLE COATING FOR GOLF BALLS LORD CORPORATION (US) 2001-12-13 WO claimed
WO-1995011927-A1 POLYESTER-MODIFIED POLYDIENE/ACRYLOURETHANE OLIGOMERS LORD CORPORATION (US) 1995-05-04 WO claimed
CN-109415353-B Pegylated carfilzomib compounds 美国安进公司 2023-01-10 CN disclosed
EP-3464277-B1 PEGYLATED CARFILZOMIB COMPOUNDS AMGEN INC (US) 2022-12-28 EP disclosed
US-11077198-B2 Pegylated carfilzomib compounds AMGEN INC. (US) 2021-08-03 US disclosed
US-11077198-B2 Pegylated carfilzomib compounds AMGEN INC. (US) 2021-08-03 US disclosed
US-10953626-B2 Coated articles and methods for making the same AXALTA COATING SYSTEMS IP CO., LLC (US) 2021-03-23 US disclosed
US-20200376131-A1 Pegylated Carfilzomib Compounds AMGEN INC. (US) 2020-12-03 US disclosed
US-20200376131-A1 Pegylated Carfilzomib Compounds AMGEN INC. (US) 2020-12-03 US disclosed
US-4198200-A THERMOSETTING ADDITION-POLYMERIZED UNSATURATED URETHANE OR UREA RESIN, PHOTOFLASH GLASS COATING LORD CORPORATION (US) 1980-04-15 US disclosed
US-4119640-A ACRYLIC OR METHACRYLIC ACID, DIEPOXIDES, INKS, HEAT OR RADIATION CURABLE COATINGS UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4112017-A UNSATURATED ADDITION POLYMERIZABLE URETHANE RESINS LORD CORPORATION (US) 1978-09-05 US disclosed
US-4100046-A Radiation polymerizable cycloalkenyl derivatives of acrylated epoxidized fatty oils or fatty acids UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed
US-4066582-A IMPROVED ACRYLATE BASED RADIATION CURABLE COATING COMPOSITIONS CONTAINING NITROCELLULOSE UNION CARBIDE CORPORATION (US) 1978-01-03 US disclosed
US-3996394-A PHOTOPOLYMERIZATION UNION CARBIDE CORPORATION (US) 1976-12-07 US disclosed
US-3966572-A Photocurable low gloss coatings containing silica and acrylic acid UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed
US-3943103-A CONTAI UNION CARBIDE CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200376131-A1 Pegylated Carfilzomib Compounds FCGRT, EPOR, MCL1 KMT2A 746/4885CFD 2561/4885ALDH1A1 1647/4885
US-11077198-B2 Pegylated carfilzomib compounds FCGRT, EPOR, MCL1 KMT2A 746/4885CFD 2561/4885ALDH1A1 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.