Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869275 | 1.00 | CA1 (0.37) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL22869276 | 1.00 | CA1 (0.37) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL19557134 | 1.00 | CA1 (0.37) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL28976506 | 1.00 | CA1 (0.37) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL19557123 | 1.00 | CA1 (0.37) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL22869421 | 0.82 | TRPM8 (0.45) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL19321648 | 0.82 | TRPM8 (0.45) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL13748535 | 0.82 | TRPM8 (0.45) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL19321646 | 0.82 | TRPM8 (0.45) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL1030989 | 0.82 | CA1 (0.38) | CA1CA2CA12CA9CAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194721-A1 | DIFLUOROALKYLCYCLOPROPYL AMINO ACIDS AND ESTERS, AND SYNTHESES THEREOF | ABBVIE INC. | 2018-07-12 | — | — | US | disclosed |
| US-20180057482-A1 | SYNTHETIC ROUTE TO ANTI-VIRAL AGENTS | ABBVIE INC. | 2018-03-01 | — | — | US | disclosed |
| US-9809576-B1 | Synthetic route to anti-viral agents | ABBVIE INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809534-B1 | Difluoroalkylcyclopropyl amino acids and esters, and syntheses thereof | ABBVIE INC. (US) | 2017-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194721-A1 | DIFLUOROALKYLCYCLOPROPYL AMINO ACIDS AND ESTERS, AND SYNTHESES THEREOF | DNPEP, PEPD, ANPEP | CA1 687/4885CA2 1757/4885CA12 1614/4885 |
| US-20180057482-A1 | SYNTHETIC ROUTE TO ANTI-VIRAL AGENTS | ACE, ACE2, PREP | CA1 1971/4885CA2 2697/4885CA12 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.