Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584756 | 0.85 | GAA (0.56) | GAACYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL12191687 | 0.84 | ALDH1A1 (0.45) | GAACYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL2497072 | 0.83 | HTT (0.44) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4432103 | 0.82 | ALDH1A1 (0.35) | GAAKDM4EALDH1A1CYP3A4MEN1 | |
| SCHEMBL5473563 | 0.79 | SKP2 (0.49) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL31090146 | 0.78 | GAA (0.77) | GAACYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL2366928 | 0.77 | GFER (0.45) | CYP19A1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL30168383 | 0.74 | ALDH1A1 (0.56) | GAACYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL358600 | 0.74 | ALDH1A1 (0.56) | GAACYP19A1ATMKDM4EALDH1A1 | |
| SCHEMBL24197444 | 0.73 | TAAR1 (0.44) | KDM4EALDH1A1KMT2ACYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809668-B2 | Polymerizable compound, composition, polymer, optically anisotropic body, liquid crystal display device, and organic EL device | DIC CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |