Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 7/20 | 0.48 |
| ▸ | SELP | P16109 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRAS | P01112 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312768 | 0.92 | SELE (0.48) | SELESELPPTPN1 | |
| SCHEMBL13312082 | 0.87 | SELE (0.62) | SELESELP | |
| SCHEMBL16257568 | 0.86 | SELE (0.60) | SELESELP | |
| SCHEMBL15434745 | 0.86 | SELE (0.59) | SELESELP | |
| SCHEMBL16257616 | 0.85 | SELE (0.58) | SELESELP | |
| SCHEMBL13969719 | 0.84 | SELE (0.51) | SELESELP | |
| SCHEMBL15434743 | 0.84 | SELE (0.40) | SELESELPPTPN1 | |
| SCHEMBL3006760 | 0.82 | SELE (0.57) | SELESELP | |
| SCHEMBL13017796 | 0.81 | SELE (0.52) | SELESELP | |
| SCHEMBL12240500 | 0.80 | SELE (0.48) | SELESELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264043-B1 | Heterobifunctional pan-selectin inhibitors | GLYCOMIMETICS INC (US) | 2017-11-08 | — | — | EP | disclosed |