⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19217588 | 0.87 | PPARG (0.32) | — | |
| SCHEMBL19559794 | 0.74 | — | — | |
| SCHEMBL16491937 | 0.68 | PPARG (0.45) | — | |
| SCHEMBL6931095 | 0.68 | PPARG (0.45) | — | |
| SCHEMBL14213680 | 0.67 | PPARG (0.41) | — | |
| SCHEMBL16489283 | 0.67 | PPARG (0.41) | — | |
| SCHEMBL6928360 | 0.66 | PPARG (0.36) | — | |
| SCHEMBL14213688 | 0.66 | PPARG (0.33) | — | |
| SCHEMBL19559811 | 0.64 | PPARG (0.52) | — | |
| SCHEMBL19559771 | 0.61 | PPARG (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513070-B1 | PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES | CIRIUS THERAPEUTICS INC (US) | 2017-11-08 | — | — | EP | disclosed |