Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559715 | 0.87 | — | — | |
| SCHEMBL16491937 | 0.81 | PPARG (0.45) | PPARGMEN1LMNATSHRALOX12 | |
| SCHEMBL6931095 | 0.81 | PPARG (0.45) | PPARGMEN1LMNATSHRALOX12 | |
| SCHEMBL6928360 | 0.79 | PPARG (0.36) | PPARGMEN1LMNATSHRALOX12 | |
| SCHEMBL17546497 | 0.70 | PPARG (0.45) | PPARGMEN1LMNATSHRKMT2A | |
| SCHEMBL6931373 | 0.70 | PPARG (0.35) | PPARGMEN1LMNAKMT2A | |
| SCHEMBL6931166 | 0.70 | PPARG (0.48) | PPARGLMNA | |
| SCHEMBL6931096 | 0.70 | PPARG (0.48) | PPARGLMNA | |
| SCHEMBL19217746 | 0.70 | PPARG (0.49) | PPARGMEN1TSHRKMT2A | |
| SCHEMBL16491938 | 0.69 | PPARG (0.45) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |