Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557666 | 0.92 | TLR8 (0.34) | KCNH2TLR8TLR7 | |
| SCHEMBL22734102 | 0.78 | GLP1R (0.33) | — | |
| SCHEMBL22734107 | 0.78 | GLP1R (0.33) | — | |
| SCHEMBL22734103 | 0.78 | GLP1R (0.33) | — | |
| SCHEMBL186950 | 0.77 | — | — | |
| SCHEMBL22734106 | 0.77 | GAA (0.37) | ADORA1 | |
| SCHEMBL22734117 | 0.75 | KMT2A (0.34) | — | |
| SCHEMBL22734113 | 0.74 | LMNA (0.37) | ADORA1 | |
| SCHEMBL22734119 | 0.73 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL22734111 | 0.72 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400962-B1 | Medicinal combinations containing PDE4 inhibitors and NSAIDS | BOEHRINGER INGELHEIM INT (DE) | 2017-11-08 | — | — | EP | disclosed |