Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC1 | P48995 | 1/20 | 0.49 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.49 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560365 | 0.92 | TRPC1 (0.46) | TRPC1TRPC4TRPC5CHRM5P2RX3 | |
| SCHEMBL19560455 | 0.92 | TRPC5 (0.45) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL21316291 | 0.88 | TRPC5 (0.54) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL19505311 | 0.86 | TRPC5 (0.53) | TRPC1TRPC4TRPC5CHRM5P2RX3 | |
| SCHEMBL19505209 | 0.86 | TRPC5 (0.52) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL19505055 | 0.86 | TRPC5 (0.56) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL21499665 | 0.85 | TRPC5 (0.51) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL18833641 | 0.85 | TRPC5 (0.51) | TRPC1TRPC4TRPC5HCRTR1HCRTR2 | |
| SCHEMBL19505138 | 0.85 | TRPC5 (0.43) | TRPC1TRPC4TRPC5CHRM5HCRTR1 | |
| SCHEMBL19505445 | 0.84 | TRPC5 (0.51) | TRPC1TRPC4TRPC5CHRM5HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970316-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-11-08 | — | — | EP | disclosed |