Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334289 | 0.78 | PARP10 (0.57) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL162032 | 0.75 | HTR2C (0.57) | MLNRCYP2D6 | |
| SCHEMBL22995086 | 0.75 | PARP10 (0.63) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL12151268 | 0.75 | PARP10 (0.57) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL30468509 | 0.75 | DRD2 (0.55) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL2061785 | 0.75 | CA9 (0.46) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL5040462 | 0.75 | DRD2 (0.55) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL30468395 | 0.75 | CA9 (0.46) | PARP11PARP10PARP1F7F3 | |
| SCHEMBL8892613 | 0.74 | SMN1; SMN2 (0.43) | PARP11PARP10PARP1F7F3 | |
| Bromide SCHEMBL174563 | 0.74 | HTR2C (0.55) | MLNRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332920-A2 | Processes for preparing 3-benzazepines | Arena Pharmaceuticals, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |