Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435497 | 0.74 | SLC22A12 (0.54) | SLC22A12IMPDH2IMPDH1DNMT1CA1 | |
| SCHEMBL19435572 | 0.74 | SLC22A12 (0.51) | SLC22A12ANPEPIMPDH2IMPDH1DNMT1 | |
| SCHEMBL19435574 | 0.73 | IMPDH2 (0.64) | SLC22A12IMPDH2IMPDH1CA1CA2 | |
| SCHEMBL13948301 | 0.70 | CA1 (0.53) | SLC22A12ANPEPIMPDH2IMPDH1DNMT1 | |
| SCHEMBL29039496 | 0.70 | CA1 (0.50) | SLC22A12DNMT1CA1CA2 | |
| SCHEMBL2353695 | 0.69 | CA1 (0.53) | SLC22A12IMPDH2IMPDH1CA1CA2 | |
| SCHEMBL16917824 | 0.68 | IMPDH2 (0.57) | SLC22A12IMPDH2IMPDH1CA1CA2 | |
| SCHEMBL271166 | 0.68 | TDP1 (0.45) | — | |
| SCHEMBL6547337 | 0.68 | TSHR (0.50) | — | |
| SCHEMBL19435545 | 0.68 | SLC22A12 (0.57) | SLC22A12IMPDH2IMPDH1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241822-A1 | URAT1 INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2017-11-08 | — | — | EP | disclosed |