Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OGT | O15294 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675668 | 0.69 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL13615467 | 0.65 | MAPT (0.45) | KDM4EOGTUSP2MAPTRECQL | |
| SCHEMBL6745671 | 0.63 | — | — | |
| SCHEMBL20068344 | 0.61 | — | — | |
| SCHEMBL13219039 | 0.60 | — | — | |
| SCHEMBL24413828 | 0.58 | MAPT (0.66) | KDM4EMAPTBLM | |
| SCHEMBL2261888 | 0.58 | SMN1; SMN2 (0.68) | KDM4EMAPT | |
| SCHEMBL17655672 | 0.58 | — | — | |
| SCHEMBL22332049 | 0.55 | — | — | |
| SCHEMBL3650457 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969696-B2 | Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof | INDIAN INSTITUTE OF SCIENCE (IN) | 2018-05-15 | — | — | US | disclosed |
| US-9828342-B2 | Isatin derivatives, pharmaceutical compositions thereof, and methods of use thereof | CITY OF HOPE (US) | 2017-11-28 | — | — | US | disclosed |
| EP-3027605-B1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-11-08 | — | — | EP | disclosed |