Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | OGT | O15294 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675668 | 0.81 | SMN1; SMN2 (0.31) | METAP1 | |
| SCHEMBL6745671 | 0.74 | — | — | |
| SCHEMBL12645490 | 0.74 | — | — | |
| SCHEMBL5487108 | 0.73 | MAPT (0.47) | MAPTKDM4EOGTUSP2RECQL | |
| SCHEMBL20362831 | 0.72 | MAPT (0.41) | MAPTKDM4EOGTUSP2RECQL | |
| SCHEMBL123424 | 0.69 | — | — | |
| SCHEMBL12014049 | 0.69 | METAP1 (0.45) | MAPTKDM4EOGTUSP2RECQL | |
| SCHEMBL4428107 | 0.65 | METAP1 (0.80) | MAPTKDM4EMETAP1KMT2APOLB | |
| SCHEMBL19563003 | 0.65 | KDM4E (0.33) | MAPTKDM4EOGTUSP2RECQL | |
| SCHEMBL12013780 | 0.65 | METAP1 (0.46) | MAPTKDM4EOGTUSP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870624-B2 | Histone deacetylase inhibitors | KARUS THERAPEUTICS LIMITED (GB) | 2020-12-22 | — | — | US | disclosed |
| US-20180170876-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS | KARUS THERAPEUTICS LIMITED (GB) | 2018-06-21 | — | — | US | disclosed |
| US-9878998-B2 | Barbiturate and thiobarbiturate compounds for use in cancer therapy | NUHOPE LLC (US) | 2018-01-30 | — | — | US | disclosed |
| US-9567305-B2 | Quinoxaline compounds and derivatives | SOUTHERN METHODIST UNIVERSITY (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160235752-A1 | COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT | UNIVERSITY OF NEW ORLEANS (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| WO-2016094688-A1 | FUSED 1,3-AZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-16 | — | — | WO | disclosed |
| US-9190617-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-9190617-B2 | Photoelectric conversion element and solar cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20130125987-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR BATTERY CONTAINING THE SAME | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130125987-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR BATTERY CONTAINING THE SAME | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130025682-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-01-31 | — | — | US | disclosed |
| US-20130025682-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-01-31 | — | — | US | disclosed |
| US-20120325319-A1 | PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-12-27 | — | — | US | disclosed |
| US-20120325319-A1 | PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-12-27 | — | — | US | disclosed |
| EP-2116585-A1 | ULTRAVIOLET ABSORBER COMPOSITION | Fujifilm Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | MAPT 2226/4885KDM4E 2657/4885OGT 2553/4885 |
| US-20160235752-A1 | COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT | LIPA, ELANE, CLPP | MAPT 3305/4885KDM4E 3871/4885OGT 588/4885 |
| US-20180170876-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC5, HDAC11 | MAPT 1987/4885KDM4E 146/4885OGT 2694/4885 |
| US-10870624-B2 | Histone deacetylase inhibitors | HDAC1, HDAC5, HDAC2 | MAPT 1674/4885KDM4E 133/4885OGT 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.