Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125307 | 0.81 | ALDH1A1 (0.65) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10341785 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19905402 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1MAPTHPGDALOX12 | |
| Acetanilide SCHEMBL21056245 | 0.75 | NAPRT (0.86) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11888597 | 0.75 | NPC1 (0.76) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3667956 | 0.75 | KMT2A (0.69) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL307601 | 0.74 | MAPT (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NAPRT | |
| SCHEMBL588524 | 0.74 | HPGD (0.86) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL28361814 | 0.74 | MEN1 (0.55) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4696809 | 0.74 | NAMPT (0.65) | RAB9ASMN1; SMN2NPC1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017193034-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES (US) | 2017-11-09 | — | — | WO | disclosed |