Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1944828 | 1.00 | LIPE (0.61) | LIPEEGLN1 | |
| SCHEMBL610547 | 1.00 | LIPE (0.61) | LIPEEGLN1 | |
| SCHEMBL11679 | 0.87 | LIPE (0.64) | LIPEEGLN1 | |
| SCHEMBL11294 | 0.87 | LIPE (0.64) | LIPEEGLN1 | |
| SCHEMBL9889 | 0.87 | LIPE (0.64) | LIPEEGLN1 | |
| SCHEMBL5787 | 0.85 | LIPE (0.62) | LIPE | |
| SCHEMBL1590925 | 0.85 | LIPE (0.62) | LIPEEGLN1 | |
| SCHEMBL12068 | 0.85 | LIPE (0.62) | LIPEEGLN1 | |
| SCHEMBL11682 | 0.85 | LIPE (0.62) | LIPE | |
| SCHEMBL11902 | 0.85 | LIPE (0.62) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507239-A1 | AZACYCLIC SPIRO DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067166-A1 | AZACYCLIC SPIRO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |