Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238072 | 0.87 | HTT (0.62) | HTTKDM4EHSD17B10HPGDALB | |
| SCHEMBL8432348 | 0.85 | HTT (0.56) | HTTKDM4EHSD17B10HPGDALB | |
| SCHEMBL446113 | 0.83 | HTT (0.77) | HTTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL29682980 | 0.83 | HTT (0.77) | HTTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL5359012 | 0.82 | MRGPRX4 (0.48) | HPGDALBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29839667 | 0.81 | HTT (0.81) | HTTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL8434168 | 0.81 | HTT (0.81) | HTTKDM4EHSD17B10HPGDMAPT | |
| Hydrochloric Acid SCHEMBL9633469 | 0.81 | HTT (0.74) | HTTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL30689523 | 0.79 | ALB (0.50) | HTTKDM4EHSD17B10HPGDALB | |
| SCHEMBL17274980 | 0.79 | PTPN1 (0.46) | HTTKDM4ECES2CES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116367842-A | Application of thymidine derivative in preparing medicine | 上海岸阔医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2020043185-A1 | APPLICATION OF AMINO ACID NUTRIENT, AND PHARMACEUTICAL COMPOSITION INCLUDING AMINO ACID NUTRIENT | 成都夸常奥普医疗科技有限公司 | 2020-03-05 | — | — | WO | disclosed |
| WO-2014137301-A1 | HYDRAZONES AND THIAZOLIDINONES DERIVED FROM DIFLUNISAL | KUCUKGUZEL SUKRIYE GUNIZ (TR) | 2014-09-12 | — | — | WO | disclosed |
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011068560-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |