SCHEMBL446113

SCHEMBL446113

O=C(O)c1ccccc1Oc1ccccc1C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.77
KDM4E B2RXH2 9/20 0.63
ALDH1A1 P00352 9/20 0.63
HSD17B10 Q99714 6/20 0.63
HPGD P15428 6/20 0.63
HMGB1 P09429 2/20 0.63
NAPRT Q6XQN6 2/20 0.63
ESR1 P03372 1/20 0.63
ITGB3 P05106 1/20 0.63
ITGA2B P08514 1/20 0.63
TSHR P16473 1/20 0.63
GGT1 P19440 1/20 0.63
PTGS1 P23219 1/20 0.63
PTGS2 P35354 1/20 0.63
BLM P54132 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
ALOX15 P16050 1/20 0.62
MAPT P10636 2/20 0.61
USP2 O75604 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29682980 1.00 HTT (0.77) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL29839667 0.98 HTT (0.81) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL8434168 0.98 HTT (0.81) HTTKDM4EALDH1A1HSD17B10HPGD
Hydrochloric Acid SCHEMBL9633469 0.98 HTT (0.74) HTTKDM4EALDH1A1HSD17B10HPGD
Ethylene SCHEMBL8620063 0.95 HTT (0.71) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL713317 0.91 HTT (0.67) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL3826756 0.89 HTT (0.65) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL1270519 0.89 HTT (0.65) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL1537710 0.89 HTT (0.70) HTTKDM4EALDH1A1HSD17B10HPGD
SCHEMBL28411450 0.89 CTNNB1 (0.66) HTTKDM4EALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 864 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736576-B Fireproof polyamide composition and preparation method and application thereof 江苏晋伦塑料科技有限公司 2025-03-25 CN claimed
CN-117736576-A Fireproof polyamide composition and preparation method and application thereof 江苏晋伦塑料科技有限公司 2024-03-22 CN claimed
CN-114410108-B Halogen-free flame-retardant semi-aromatic polyamide composition, and preparation method and application thereof 江苏晋伦塑料科技有限公司 2023-10-27 CN claimed
CN-114410108-A Halogen-free flame-retardant semi-aromatic polyamide composition and preparation method and application thereof 江苏晋伦塑料科技有限公司 2022-04-29 CN claimed
US-10913718-B2 Synthesis and characterization of metal organic frameworks KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2021-02-09 US claimed
CN-104311408-B The preparation method of 4,4 '-oxydibenzoic acids 沈阳化工研究院有限公司 2019-11-08 CN claimed
CN-106832311-B Eu-MOF multicolor luminous crystal material, Tb-MOF green light crystal material and preparation method thereof 南京工业大学 2019-11-05 CN claimed
CN-106835334-B Leafy FDY, hollow shape polyester fiber of one kind and preparation method thereof 江苏恒科新材料有限公司 2019-10-01 CN claimed
CN-106835336-B A kind of FDY, square hollow polyester fiber and preparation method thereof 江苏恒科新材料有限公司 2019-08-27 CN claimed
CN-106801265-B Hollow FDY, shape polyester fiber of 8 words of one kind and preparation method thereof 江苏恒科新材料有限公司 2019-08-27 CN claimed
EP-0540653-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1993-05-12 EP claimed
US-5138020-A PHOSPHATE SALTS OF MONOMERS FOR PBZ AND THEIR USE IN PREPARING PBZ POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-08-11 US claimed
EP-0390908-A4 BLENDS OF LIQUID CRYSTALLINE POLYMERS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) P-HYDROXYBENZOIC ACID POLYMERS AND ANOTHER LCP CONTAINING OXYBISBENZENE AND NAPHTHALENE DERIVATIVES 1992-07-08 EP claimed
WO-1992001662-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1992-02-06 WO claimed
EP-0390908-A1 BLENDS OF LIQUID CRYSTALLINE POLYMERS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) p-HYDROXYBENZOIC ACID POLYMERS AND ANOTHER LCP CONTAINING OXYBISBENZENE AND NAPHTHALENE DERIVATIVES AMOCO CORPORATION (US) 1990-10-10 EP claimed
WO-1990004002-A1 BLENDS OF LIQUID CRYSTALLINE POLYMERS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) p-HYDROXYBENZOIC ACID POLYMERS AND ANOTHER LCP CONTAINING OXYBISBENZENE AND NAPHTHALENE DERIVATIVES AMOCO CORPORATION (US) 1990-04-19 WO claimed
EP-0000097-B1 POLYARYLENE ESTERS MOULDING COMPOSITIONS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES THEREFROM MONSANTO COMPANY (US) 1981-02-11 EP claimed
US-4199493-A REINFORCING AGENT AND THERMOPLASTIC VINYL ADDITION POLYMER MONSANTO COMPANY (US) 1980-04-22 US claimed
EP-0000097-A1 Polyarylene esters moulding compositions, process for their preparation and shaped articles therefrom MONSANTO COMPANY (US) 1978-12-20 EP claimed
US-4127557-A PHENOL-TETRACHLOROETHANE SOLVENT MONSANTO COMPANY (US) 1978-11-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10913718-B2 Synthesis and characterization of metal organic frameworks OSTC, ORC3, COXFA4 HTT 4226/4885KDM4E 3237/4885ALDH1A1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.