⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620412 | 0.83 | CA1 (0.36) | — | |
| SCHEMBL2532886 | 0.82 | — | — | |
| SCHEMBL2528919 | 0.80 | GPR84 (0.46) | — | |
| SCHEMBL9475366 | 0.79 | — | — | |
| SCHEMBL18269439 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL2528854 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL25834870 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL7582371 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL25834774 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL9947521 | 0.78 | GPR84 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| US-12473295-B2 | Substituted straight chain spiro derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2025-11-18 | — | — | US | disclosed |
| US-20250333421-A1 | PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES | JANSSEN PHARMACEUTICA NV (BE) | 2025-10-30 | — | — | US | disclosed |
| CN-118344372-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255773-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118255774-A | Substituted straight-chain spiro derivatives | 詹森药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-4347600-A1 | PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES | JANSSEN Pharmaceutica NV (BE) | 2024-04-10 | — | — | EP | disclosed |
| CN-117425659-A | Pyridazine or 1,2, 4-triazines substituted by spirocyclic amines | 詹森药业有限公司 | 2024-01-19 | — | — | CN | disclosed |
| US-11718758-B2 | Aqueous dispersion of colored particles | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2023-08-08 | — | — | US | disclosed |
| US-20050107334-A1 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use | XENOPORT, INC. | 2005-05-19 | — | — | US | disclosed |
| WO-2005019163-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-0971904-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |
| EP-0521650-B1 | Working fluid composition for use in refrigeration system | KAO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5401433-A | Base oils with ketone groups for use with hydrofluorocarbons, air conditioners | KAO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5300245-A | Mixed with hydrofluorocarbons | KAO CORPORATION (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0521650-A1 | Working fluid composition for use in refrigeration system | Kao Corporation (JP) | 1993-01-07 | — | — | EP | disclosed |
| EP-0426436-A2 | Preparation of ketone containing photodegradable polymers | THE DOW CHEMICAL COMPANY (US) | 1991-05-08 | — | — | EP | disclosed |