Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 10/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630195 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KAT2BBPTFKDM4E | |
| SCHEMBL27630196 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KAT2BBPTFKDM4E | |
| SCHEMBL18912152 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KAT2BBPTFKDM1A | |
| SCHEMBL19575583 | 0.91 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KAT2BBPTFKDM4E | |
| SCHEMBL21872432 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KAT2BBPTFKDM1A | |
| SCHEMBL25103790 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KAT2BBPTFKDM1A | |
| SCHEMBL19575589 | 0.91 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KAT2BBPTFKDM1A | |
| SCHEMBL18379139 | 0.91 | KDM1A (0.42) | ALDH1A1HSD17B10KAT2BKDM1ANCF1 | |
| SCHEMBL18379222 | 0.91 | KDM1A (0.42) | ALDH1A1HSD17B10KAT2BKDM1ANCF1 | |
| SCHEMBL14472409 | 0.91 | KDM1A (0.42) | ALDH1A1HSD17B10KAT2BKDM1ANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191599-A1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |