Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 17/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21004288 | 0.87 | TAS2R14 (0.50) | TAS2R14SYK | |
| SCHEMBL21004286 | 0.83 | TAS2R14 (0.47) | TAS2R14SYK | |
| SCHEMBL19575435 | 0.78 | PLK1 (0.60) | TAS2R14SYK | |
| SCHEMBL19554381 | 0.76 | SYK (0.55) | TAS2R14SYK | |
| SCHEMBL21004276 | 0.76 | SYK (0.50) | TAS2R14SYK | |
| SCHEMBL21004275 | 0.74 | TAS2R14 (0.46) | TAS2R14SYK | |
| SCHEMBL19553899 | 0.73 | SYK (0.55) | TAS2R14SYK | |
| SCHEMBL16750016 | 0.73 | SYK (0.71) | SYK | |
| SCHEMBL21004550 | 0.72 | SYK (0.49) | TAS2R14SYK | |
| SCHEMBL3265212 | 0.72 | SYK (0.49) | TAS2R14SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452465-B1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2020-11-04 | — | — | EP | disclosed |
| WO-2017191599-A1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |