Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.40 |
| ▸ | CHKB | Q9Y259 | 2/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575485 | 0.91 | HDAC1 (0.42) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL20973069 | 0.85 | HDAC1 (0.39) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL19575675 | 0.84 | HDAC1 (0.46) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL20973044 | 0.83 | JAK2 (0.38) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL20973055 | 0.83 | NT5E (0.45) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL19575514 | 0.82 | HDAC1 (0.44) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL19575481 | 0.81 | HDAC1 (0.41) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL19574919 | 0.81 | HDAC1 (0.46) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL19575665 | 0.80 | HDAC1 (0.42) | CHKAHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL26213820 | 0.80 | HDAC1 (0.45) | CHKAHDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |