Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575481 | 0.90 | HDAC1 (0.41) | NT5EHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL19575685 | 0.89 | HDAC1 (0.42) | NT5EHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL20973069 | 0.89 | HDAC1 (0.39) | NT5EHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL19575675 | 0.88 | HDAC1 (0.46) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL19575684 | 0.87 | HDAC1 (0.42) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL20973044 | 0.87 | JAK2 (0.38) | NT5EHDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL19574996 | 0.87 | HDAC1 (0.44) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL19575485 | 0.87 | HDAC1 (0.42) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL19575514 | 0.86 | HDAC1 (0.44) | HDAC1HDAC6HDAC2HDAC3HDAC4 | |
| SCHEMBL19574919 | 0.85 | HDAC1 (0.46) | NT5EHDAC1HDAC6HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | B.C.I. PHARMA (BE) | 2022-02-01 | — | — | US | disclosed |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | ADK, TNNI3K, TNK2 | NT5E 849/4885HDAC1 1343/4885HDAC6 2991/4885 |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ADK, TNNI3K, TNK2 | NT5E 849/4885HDAC1 1343/4885HDAC6 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.