Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575673 | 0.91 | HDAC1 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19575728 | 0.90 | YTHDC1 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19575474 | 0.88 | HDAC1 (0.40) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL20975209 | 0.84 | TDP1 (0.42) | ADORA2AADORA1 | |
| SCHEMBL19575675 | 0.84 | HDAC1 (0.46) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL26225007 | 0.83 | HDAC1 (0.36) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19575381 | 0.83 | CHKA (0.46) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19575629 | 0.82 | SERPINA3 (0.42) | TMIGD3ADORA2AADORA1ADORA2BHRH4 | |
| SCHEMBL19575370 | 0.82 | ADORA2A (0.39) | HDAC1HDAC4HDAC6CDK2TMIGD3 | |
| SCHEMBL19575514 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |