Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20946423 | 0.94 | SGMS1 (0.43) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19575400 | 0.94 | HDAC1 (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19575382 | 0.93 | HDAC1 (0.43) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20975096 | 0.93 | NAMPT (0.42) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20974552 | 0.92 | HDAC1 (0.39) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20974949 | 0.92 | NAMPT (0.41) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20974951 | 0.91 | HDAC1 (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20974950 | 0.90 | HDAC1 (0.41) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20972941 | 0.90 | HDAC1 (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20975036 | 0.90 | CYP19A1 (0.41) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | B.C.I. PHARMA (BE) | 2022-02-01 | — | — | US | disclosed |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2019-05-02 | — | — | US | disclosed |
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | ADK, TNNI3K, TNK2 | HDAC1 1343/4885HDAC6 2991/4885HDAC3 1640/4885 |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ADK, TNNI3K, TNK2 | HDAC1 1343/4885HDAC6 2991/4885HDAC3 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.