Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.56 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 17/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29718827 | 0.86 | P2RX4 (0.71) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19552065 | 0.86 | P2RX4 (0.71) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL24766678 | 0.86 | P2RX4 (0.62) | CA12CA1CA2CA9KCNJ6 | |
| SCHEMBL19576993 | 0.80 | P2RX4 (0.49) | CA12CA1CA2CA9KCNJ6 | |
| SCHEMBL19576956 | 0.79 | P2RX4 (0.49) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19576510 | 0.78 | P2RX4 (0.46) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19576804 | 0.78 | KCNJ5 (0.62) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19576513 | 0.77 | P2RX4 (0.44) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19576503 | 0.77 | P2RX4 (0.49) | KCNJ6KCNJ5KCNJ3P2RX4 | |
| SCHEMBL19575900 | 0.77 | P2RX4 (0.46) | KCNJ6KCNJ5KCNJ3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |
| WO-2017191000-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | WO | disclosed |