Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 11/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894338 | 0.86 | P2RX4 (0.68) | P2RX4LMNAALDH1A1 | |
| SCHEMBL24766678 | 0.86 | P2RX4 (0.62) | P2RX4NPC1RAB9ACA1CA2 | |
| SCHEMBL29716996 | 0.78 | P2RX4 (0.54) | P2RX4NPC1RAB9ACA1CA2 | |
| SCHEMBL19551955 | 0.78 | P2RX4 (0.54) | P2RX4NPC1RAB9ACA1CA2 | |
| SCHEMBL19551956 | 0.78 | P2RX4 (0.55) | P2RX4NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29716926 | 0.78 | P2RX4 (0.55) | P2RX4NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL19551916 | 0.77 | P2RX4 (0.53) | P2RX4NPC1RAB9ACA1CA2 | |
| SCHEMBL20240948 | 0.77 | P2RX4 (0.53) | P2RX4NPC1RAB9ACA1CA2 | |
| SCHEMBL18301859 | 0.77 | P2RX4 (0.82) | P2RX4 | |
| SCHEMBL31290144 | 0.77 | P2RX4 (0.82) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191000-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | WO | disclosed |