Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 12/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258418 | 0.88 | P2RX4 (0.59) | P2RX4LMNAALDH1A1 | |
| SCHEMBL20240937 | 0.80 | P2RX4 (0.59) | P2RX4LMNAALDH1A1 | |
| SCHEMBL20240923 | 0.80 | P2RX4 (0.56) | P2RX4LMNAALDH1A1 | |
| SCHEMBL20243158 | 0.79 | P2RX4 (0.58) | P2RX4 | |
| SCHEMBL24766678 | 0.79 | P2RX4 (0.62) | P2RX4ANO1NPC1RAB9ALMNA | |
| SCHEMBL20241201 | 0.78 | P2RX4 (0.64) | P2RX4NPC1RAB9A | |
| SCHEMBL19576905 | 0.77 | P2RX4 (0.60) | P2RX4ANO1NPC1RAB9ALMNA | |
| SCHEMBL24766610 | 0.76 | P2RX4 (0.50) | P2RX4ANO1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20243503 | 0.75 | P2RX4 (0.49) | P2RX4 | |
| SCHEMBL20240919 | 0.74 | P2RX4 (0.59) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018104305-A1 | FIELD OF APPLICATION OF THE INVENTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | claimed |
| WO-2018104305-A1 | FIELD OF APPLICATION OF THE INVENTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | disclosed |