⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202645 | 0.82 | SMPD1 (0.30) | — | |
| SCHEMBL21474777 | 0.82 | SMPD1 (0.30) | — | |
| SCHEMBL21202641 | 0.81 | FBP1 (0.34) | — | |
| SCHEMBL10051004 | 0.81 | FBP1 (0.34) | — | |
| SCHEMBL10005831 | 0.81 | FBP1 (0.34) | — | |
| SCHEMBL19577795 | 0.78 | — | — | |
| SCHEMBL13172425 | 0.75 | FBP1 (0.36) | — | |
| SCHEMBL16996706 | 0.75 | FBP1 (0.36) | — | |
| SCHEMBL12523685 | 0.72 | SMPD1 (0.41) | — | |
| SCHEMBL18892768 | 0.72 | SMPD1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213541-B2 | Antisense-oligonucleotides as inhibitors of TGF-R signaling | Neurovision Pharma GmbH (DE) | 2022-01-04 | — | — | US | disclosed |
| US-20170319614-A1 | ANTISENSE-OLIGONUCLEOTIDES AS INHIBITORS OF TGF-R SIGNALING | Neurovision Pharma GmbH (DE) | 2017-11-09 | — | — | US | disclosed |