Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.44 |
| ▸ | KDM1A | O60341 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579978 | 0.96 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1APPARGROCK2 | |
| SCHEMBL19580004 | 0.96 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1APPARGROCK2 | |
| SCHEMBL19579946 | 0.93 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1AMAPT | |
| SCHEMBL19579947 | 0.93 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1APPARGROCK2 | |
| SCHEMBL19579960 | 0.93 | SLC34A2 (0.49) | SLC34A2HDAC1KDM1APPARGROCK2 | |
| SCHEMBL46817 | 0.92 | KDM1A (0.51) | SLC34A2HDAC1KDM1APSMD14STAMBP | |
| SCHEMBL19579972 | 0.92 | SLC34A2 (0.49) | SLC34A2HDAC1KDM1AMAPT | |
| SCHEMBL19579948 | 0.91 | SLC34A2 (0.54) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL46688 | 0.91 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1APPARG | |
| SCHEMBL6000400 | 0.91 | SLC34A2 (0.48) | SLC34A2HDAC1KDM1APPARGROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |