Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579960 | 0.94 | SLC34A2 (0.49) | SLC34A2HDAC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19580004 | 0.93 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1A | |
| SCHEMBL19579952 | 0.92 | SLC34A2 (0.49) | SLC34A2HDAC1KDM1AMAPT | |
| SCHEMBL19580005 | 0.91 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1A | |
| SCHEMBL19579946 | 0.91 | SLC34A2 (0.51) | SLC34A2HDAC1POLBKDM1AMAPT | |
| SCHEMBL19579947 | 0.90 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1AAURKARPS6KB1 | |
| SCHEMBL46817 | 0.90 | KDM1A (0.51) | SLC34A2HDAC1KDM1AMAPK1AURKA | |
| SCHEMBL19579978 | 0.89 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1A | |
| SCHEMBL19579948 | 0.89 | SLC34A2 (0.54) | SLC34A2HDAC1ALDH1A1KDM1AMAPT | |
| SCHEMBL46688 | 0.89 | SLC34A2 (0.53) | SLC34A2HDAC1SMN1; SMN2HTTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |