Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 14/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579987 | 0.92 | SLC34A2 (0.48) | SLC34A2KDM1AHDAC1ROCK2PSMD14 | |
| SCHEMBL19580015 | 0.91 | SLC34A2 (0.49) | SLC34A2ALDH1A1LMNAHTTNPSR1 | |
| SCHEMBL19579947 | 0.90 | SLC34A2 (0.53) | SLC34A2KDM1AHDAC1ROCK2PSMD14 | |
| SCHEMBL19580004 | 0.90 | SLC34A2 (0.52) | SLC34A2KDM1AHDAC1ROCK2PSMD14 | |
| SCHEMBL46817 | 0.89 | KDM1A (0.51) | SLC34A2KDM1AHDAC1PSMD14STAMBP | |
| SCHEMBL19580001 | 0.87 | SLC34A2 (0.52) | SLC34A2KDM1AHDAC1ROCK2ROCK1 | |
| SCHEMBL19579978 | 0.87 | SLC34A2 (0.51) | SLC34A2KDM1AHDAC1ROCK2ROCK1 | |
| SCHEMBL19579952 | 0.87 | SLC34A2 (0.49) | SLC34A2KDM1AHDAC1ROCK2PSMD14 | |
| SCHEMBL19579973 | 0.87 | SLC34A2 (0.53) | SLC34A2KDM1AHDAC1ROCK2ROCK1 | |
| SCHEMBL19579946 | 0.87 | SLC34A2 (0.51) | SLC34A2KDM1AHDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |