Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | STAMBP | O95630 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46817 | 0.93 | KDM1A (0.51) | SLC34A2HDAC1KDM1APSMD14STAMBP | |
| SCHEMBL19579947 | 0.91 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1APSMD14STAMBP | |
| SCHEMBL19580004 | 0.91 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1APSMD14STAMBP | |
| SCHEMBL19579973 | 0.88 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1ALMNASMN1; SMN2 | |
| SCHEMBL19579978 | 0.88 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1ACHRM3ROCK2 | |
| SCHEMBL19579987 | 0.87 | SLC34A2 (0.48) | SLC34A2HDAC1KDM1ALMNAPSMD14 | |
| SCHEMBL19580001 | 0.87 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1ALMNAROCK2 | |
| SCHEMBL19579952 | 0.87 | SLC34A2 (0.49) | SLC34A2HDAC1KDM1APSMD14STAMBP | |
| SCHEMBL19579946 | 0.87 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1ALMNAMAPT | |
| SCHEMBL16808310 | 0.86 | SLC34A2 (0.43) | SLC34A2HDAC1KDM1ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |