SCHEMBL19582000

SCHEMBL19582000

CC(C)C(N)C(=O)OCc1cccnc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.48
CYP19A1 P11511 1/20 0.48
LMNA P02545 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP3A4 P08684 2/20 0.46
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
TBXAS1 P24557 2/20 0.45
HDAC1 Q13547 1/20 0.44
RECQL P46063 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
SLC15A1 P46059 1/20 0.44
GPR132 Q9UNW8 2/20 0.44
SLC1A5 Q15758 1/20 0.44
FAAH O00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11824862 1.00 CYP17A1 (0.48) CYP17A1CYP19A1LMNAKMT2ATDP1
Hydrochloric Acid SCHEMBL11824849 0.99 CYP17A1 (0.47) CYP17A1CYP19A1LMNAKMT2ATDP1
Hydrochloric Acid SCHEMBL11824857 0.99 CYP17A1 (0.47) CYP17A1CYP19A1LMNAKMT2ATDP1
SCHEMBL11825984 0.88 KMT2A (0.50) CYP17A1CYP19A1LMNAKMT2ATDP1
Hydrochloric Acid SCHEMBL11825978 0.87 KMT2A (0.49) CYP17A1CYP19A1LMNAKMT2ATDP1
Hydrochloric Acid SCHEMBL11825975 0.87 KMT2A (0.49) CYP17A1CYP19A1LMNAKMT2ATDP1
SCHEMBL8861398 0.85 KMT2A (0.51) CYP17A1CYP19A1LMNAKMT2ATDP1
SCHEMBL22752185 0.84 KMT2A (0.53) CYP17A1CYP19A1LMNAKMT2ATDP1
SCHEMBL11831400 0.83 CYP17A1 (0.46) CYP17A1CYP19A1LMNAKMT2ATDP1
Hydrochloric Acid SCHEMBL11831393 0.82 CYP17A1 (0.45) CYP17A1CYP19A1LMNAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS INC (US) 2025-10-02 US disclosed
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2023-04-27 US disclosed
US-11578087-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2023-02-14 US disclosed
EP-3578562-B1 L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES ANACOR PHARMACEUTICALS INC (US) 2021-06-23 EP disclosed
US-20210101916-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. 2021-04-08 US disclosed
US-10882872-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2021-01-05 US disclosed
US-10562921-B2 Oxaborole esters and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2020-02-18 US disclosed
EP-3578562-A1 L-VALINATE AMIDE BENZOXABOROLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES Anacor Pharmaceuticals, Inc (US) 2019-12-11 EP disclosed
CN-109503637-A For treating the noval chemical compound of the disease of helminth 安纳考尔医药公司 2019-03-22 CN disclosed
EP-3455227-A1 OXABOROLE ESTERS AND USES THEREOF Anacor Pharmaceuticals, Inc (US) 2019-03-20 EP disclosed
CN-109153688-A Oxaborolidine esters and uses thereof 安纳考尔医药公司 2019-01-04 CN disclosed
US-20170327519-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. (US) 2017-11-16 US disclosed
WO-2017195069-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. (US) 2017-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-20230132298-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-10882872-B2 Oxaborole esters and uses thereof OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-20210101916-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-11578087-B2 Oxaborole esters and uses thereof OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-20170327519-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885
US-10562921-B2 Oxaborole esters and uses thereof OXA1L, HSD17B12, OXER1 CYP17A1 689/4885CYP19A1 699/4885LMNA 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.