SCHEMBL19583028

SCHEMBL19583028

Nc1coc(CNc2ncnc3c2ncn3C2C[C@H](O)[C@@H](CO)O2)c1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 3/20 0.61
▸ HIF1A Q16665 1/20 0.56
▸ TP53 P04637 3/20 0.51
▸ PAX8 Q06710 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ LMNA P02545 2/20 0.51
▸ ADORA3 P0DMS8 1/20 0.51
▸ MITF O75030 1/20 0.51
▸ PNP P00491 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ PDE4D Q08499 1/20 0.50
▸ PDE3A Q14432 1/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583139 0.91 SLC29A1 (0.61) SLC29A1HIF1ATP53PAX8SMN1; SMN2
SCHEMBL19582982 0.90 SLC29A1 (0.61) SLC29A1HIF1ATP53PAX8SMN1; SMN2
SCHEMBL19583000 0.90 SLC29A1 (0.61) SLC29A1HIF1A
SCHEMBL19583047 0.90 SLC29A1 (0.61) SLC29A1HIF1ATP53PAX8SMN1; SMN2
SCHEMBL19583129 0.90 SLC29A1 (0.61) SLC29A1HIF1ATP53PAX8SMN1; SMN2
SCHEMBL19582965 0.88 SLC29A1 (0.58) SLC29A1HIF1ATP53PAX8SMN1; SMN2
SCHEMBL21874996 0.86 SLC29A1 (0.67) SLC29A1TP53ADORA3
SCHEMBL13467483 0.85 SLC29A1 (0.76) SLC29A1HIF1ALMNA
SCHEMBL19582977 0.85 SLC29A1 (0.76) SLC29A1HIF1ALMNA
SCHEMBL19583031 0.84 TP53 (0.71) SLC29A1HIF1ATP53PAX8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 — — EP claimed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 — — EP claimed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 — — US claimed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 — — US claimed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 — — US claimed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 — — US claimed
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 — — EP disclosed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 — — EP disclosed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 — — US disclosed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 — — US disclosed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 — — US disclosed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF GART, DAO, GLA SLC29A1 125/4885HIF1A 2000/4885TP53 3135/4885
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof GART, DAO, GLA SLC29A1 125/4885HIF1A 2000/4885TP53 3135/4885
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNG, FUT6, GART SLC29A1 59/4885HIF1A 1239/4885TP53 2090/4885
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNG, FUT6, GART SLC29A1 59/4885HIF1A 1239/4885TP53 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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