Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136691 | 0.81 | CYP2A6 (0.61) | GRM5PYCR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8331122 | 0.81 | GRM5 (0.53) | GRM5PPARGPYCR1CYP3A4CYP1A2 | |
| SCHEMBL22485593 | 0.79 | GRM5 (0.51) | GRM5PPARGPYCR1CYP3A4EGLN1 | |
| SCHEMBL14269510 | 0.76 | GRM5 (0.49) | GRM5PPARGEGLN1MEN1ALDH1A1 | |
| SCHEMBL46288 | 0.73 | KCNH2 (0.58) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL19420119 | 0.73 | PYCR1 (0.47) | PYCR1CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5703380 | 0.73 | GRM5 (1.00) | GRM5CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL304704 | 0.72 | MAOB (0.47) | GRM5PPARGPYCR1CYP3A4NPSR1 | |
| SCHEMBL6929485 | 0.72 | CA12 (0.47) | GRM5PPARGPYCR1CYP3A4MEN1 | |
| SCHEMBL5982497 | 0.72 | MAOB (0.53) | GRM5PYCR1CYP3A4CYP1A2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875552-B | Amino-substituted 1,2, 3-triazole compound and synthesis method and application thereof | 海南师范大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-111875552-A | Amino-substituted 1,2, 3-triazole compound and synthesis method and application thereof | 海南师范大学 | 2020-11-03 | — | — | CN | disclosed |
| US-10112189-B2 | Trans-metallated MOF catalyst | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-10-30 | — | — | US | disclosed |
| US-20180280949-A1 | TRANS-METALLATED MOF CATALYST | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-10-04 | — | — | US | disclosed |
| US-9975114-B2 | Metal organic frameworks as catalysts and hydrocarbon oxidation methods thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-05-22 | — | — | US | disclosed |
| US-20170326536-A1 | METAL ORGANIC FRAMEWORKS AS CATALYSTS AND HYDROCARBON OXIDATION METHODS THEREOF | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-11-16 | — | — | US | disclosed |