Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51558 | 0.84 | TSHR (0.56) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL105694 | 0.82 | TSHR (0.55) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL752302 | 0.81 | TSHR (0.53) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL648612 | 0.80 | TSHR (0.51) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL15306387 | 0.80 | TSHR (0.51) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL10949665 | 0.80 | TSHR (0.51) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL6754394 | 0.80 | TSHR (0.51) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL28682809 | 0.80 | TSHR (0.51) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL28025837 | 0.79 | TSHR (0.50) | TSHRHPGDATMTHRBALDH1A1 | |
| SCHEMBL5369953 | 0.78 | TSHR (0.50) | TSHRHPGDATMTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555677-B1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RES AND DEVELOPMENT CORPORATION (US) | 2022-04-20 | — | — | EP | disclosed |
| CN-109475660-B | Hydrophobic intraocular lenses | 宾视研发公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-3458118-B1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RES AND DEVELOPMENT CORPORATION (US) | 2021-10-27 | — | — | EP | disclosed |
| US-10899862-B2 | Hydrophobic intraocular lens | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2021-01-26 | — | — | US | disclosed |
| US-10894111-B2 | High refractive index hydrophilic materials | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2021-01-19 | — | — | US | disclosed |
| EP-3555677-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | Benz Research And Development Corporation (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-3458118-A1 | HYDROPHOBIC INTRAOCULAR LENS | Benz Research And Development Corporation (US) | 2019-03-27 | — | — | EP | disclosed |
| US-10196470-B2 | Hydrophobic intraocular lens | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180334520-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-11-22 | — | — | US | disclosed |
| US-20180169296-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-06-21 | — | — | US | disclosed |
| WO-2018112180-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017200934-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-20170327615-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2017-11-16 | — | — | US | disclosed |