Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 20/20 | 1.00 |
| ▸ | ATR | Q13535 | 5/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 10/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605306 | 0.95 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL19585082 | 0.95 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL19585078 | 0.95 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL18631935 | 0.92 | ATM (0.97) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL29565807 | 0.92 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL18631949 | 0.92 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL18632019 | 0.91 | ATM (1.00) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL20839042 | 0.88 | ATM (0.78) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL18631996 | 0.84 | ATM (0.76) | ATMATRKCNH2MTORPIK3CA | |
| SCHEMBL18632002 | 0.84 | ATM (0.79) | ATMATRKCNH2MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017194632-A1 | IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2017-11-16 | — | — | WO | claimed |
| WO-2017194632-A1 | IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017194632-A1 | IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2017-11-16 | — | — | WO | disclosed |