SCHEMBL195850

SCHEMBL195850

Nc1cnc(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785387 1.00
SCHEMBL8127902 0.87 ALDH1A1 (0.34)
SCHEMBL7353278 0.79
SCHEMBL29960628 0.79
SCHEMBL3603993 0.79
SCHEMBL16050318 0.75
SCHEMBL18561497 0.75
SCHEMBL3183893 0.75
SCHEMBL1156177 0.75
SCHEMBL29791398 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510429-A Compound containing methyl isoxazole structure, and preparation method and application thereof 中国农业大学 2024-02-06 CN claimed
EP-1045841-B1 NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY CHOONGWAE PHARMA CORP (KR) 2002-12-04 EP claimed
US-6262083-B1 Genipin derivative having liver protection activity CHOONGWAE PHARMA CORPORATION (KR) 2001-07-17 US claimed
EP-1045841-A1 NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY Choongwae Pharma Corporation (KR) 2000-10-25 EP claimed
WO-1999023090-A1 NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY CHOONGWAE PHARMA CORPORATION (KR) 1999-05-14 WO claimed
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
US-12338226-B2 Substituted benzodiazoles and use thereof in therapy THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) 2025-06-24 US disclosed
CN-115605467-B PHD inhibitor compounds, compositions and uses thereof 阿克比治疗有限公司 2025-06-13 CN disclosed
CN-120004851-A PHD inhibitor compounds, compositions and uses thereof 阿克比治疗有限公司 2025-05-16 CN disclosed
US-12209096-B2 Compounds and compositions for inducing chondrogenesis NOVARTIS AG (CH) 2025-01-28 US disclosed
WO-2024255863-A1 AMINOPYRIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF 中山优理生物医药有限公司 2024-12-19 WO disclosed
EP-3558969-B1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-09-18 EP disclosed
EP-0828739-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1998-03-18 EP disclosed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 WO disclosed
WO-1996037494-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1996-11-28 WO disclosed
US-4756739-A Herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-12 US disclosed
EP-0147105-B1 PHOTOGRAPHIC PRODUCTS EMPLOYING NOVEL NONDIFFUSIBLE HYDRAZONE DYE-RELEASING COMPOUNDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-05-11 EP disclosed
EP-0227047-A2 Pyridine derivatives and their N-oxides, process for their preparation and their use as intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-01 EP disclosed
US-4548888-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1985-10-22 US disclosed
EP-0147105-A2 Photographic products employing novel nondiffusible hydrazone dye-releasing compounds EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-03 EP disclosed