Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20693182 | 0.92 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL22474912 | 0.92 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL20833351 | 0.89 | POLG (0.48) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL15837393 | 0.89 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL15833120 | 0.89 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL18877607 | 0.89 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL15833114 | 0.89 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL15837371 | 0.89 | POLG (0.51) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL18672097 | 0.88 | POLG (0.50) | POLGPNPFUT5POLBTGM2 | |
| SCHEMBL16368330 | 0.88 | POLG (0.50) | POLGPNPFUT5POLBTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815864-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |