Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 3/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19590310 | 0.92 | DUT (0.36) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL19590311 | 0.92 | SLC28A1 (0.37) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL19605785 | 0.90 | NT5E (0.39) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18460934 | 0.89 | DUT (0.38) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL29026476 | 0.89 | DUT (0.38) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL19590312 | 0.88 | P2RY6 (0.40) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL19590303 | 0.85 | DUT (0.36) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL19590304 | 0.84 | DUT (0.36) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL15281844 | 0.84 | NT5E (0.36) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18672125 | 0.83 | DUT (0.36) | NT5ESLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815864-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |