Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 3/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154781 | 0.76 | HINT1 (0.46) | HINT1STING1NT5EPDE3BPDE3A | |
| SCHEMBL19049891 | 0.75 | STING1 (0.52) | HINT1STING1NT5EPDE3BPDE3A | |
| SCHEMBL24049418 | 0.74 | HINT1 (0.69) | HINT1NT5EPNPGSK3ARPS6KA3 | |
| SCHEMBL22968509 | 0.74 | STING1 (0.52) | HINT1STING1NT5EPDE3BPDE3A | |
| SCHEMBL20154882 | 0.74 | STING1 (0.52) | HINT1STING1NT5EPDE3BPDE3A | |
| SCHEMBL19590179 | 0.74 | HPGD (0.54) | HINT1STING1NT5EPDE3AHPGD | |
| SCHEMBL29479255 | 0.74 | HPGD (0.54) | HINT1STING1NT5EPDE3AHPGD | |
| SCHEMBL25402409 | 0.74 | HPGD (0.54) | HINT1STING1NT5EPDE3AHPGD | |
| SCHEMBL26276132 | 0.74 | HPGD (0.54) | HINT1STING1NT5EPDE3AHPGD | |
| SCHEMBL25387704 | 0.74 | HPGD (0.54) | HINT1STING1NT5EPDE3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815864-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |