Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853834 | 1.00 | POLB (0.44) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL18574250 | 1.00 | POLB (0.44) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL14946291 | 0.91 | POLB (0.43) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL14929356 | 0.91 | POLB (0.43) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL9893412 | 0.90 | POLB (0.40) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL9893411 | 0.90 | POLB (0.40) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL25401295 | 0.84 | POLB (0.42) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL17860798 | 0.84 | POLB (0.42) | POLBMEN1USP2KMT2AP2RY2 | |
| SCHEMBL24371646 | 0.84 | GAPDH (0.37) | POLBMEN1USP2KMT2AABCB1 | |
| SCHEMBL13592886 | 0.82 | POLB (0.41) | POLBMEN1USP2KMT2AP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815864-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-11-14 | — | — | US | disclosed |