GAPDH

Glyceraldehyde-3-phosphate dehydrogenase · P04406 · GAPDH on Sugi Atlas →

20,651 patent compounds predicted against GAPDH, 14,991 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL803184 SCHEMBL803184 0.58 5/20
SCHEMBL832933 SCHEMBL832933 0.39 5/20
SCHEMBL803489 SCHEMBL803489 0.68 4/20
SCHEMBL803180 SCHEMBL803180 0.66 4/20
SCHEMBL803185 SCHEMBL803185 0.56 4/20
SCHEMBL440925 SCHEMBL440925 0.68 3/20
SCHEMBL440926 SCHEMBL440926 0.68 3/20
SCHEMBL472569 SCHEMBL472569 0.63 3/20
SCHEMBL472571 SCHEMBL472571 0.63 3/20
SCHEMBL381288 SCHEMBL381288 0.51 3/20
4-Hydroxynon-2-Enal 4-Hydroxynon-2-Enal (SCHEMBL3920) 1.00 2/20
4-Hydroxynon-2-Enal 4-Hydroxynon-2-Enal (SCHEMBL3921) 1.00 2/20
Baicalin Baicalin (SCHEMBL285081) 1.00 2/20
Baicalin Baicalin (SCHEMBL285082) 1.00 2/20
SCHEMBL177366 SCHEMBL177366 0.75 2/20
SCHEMBL591688 SCHEMBL591688 0.69 2/20
Phosphoric Acid Phosphoric Acid (SCHEMBL636534) 0.64 2/20
SCHEMBL760777 SCHEMBL760777 0.64 2/20
SCHEMBL250083 SCHEMBL250083 0.61 2/20
2-Methoxy-1,4-Naphthoquinone 2-Methoxy-1,4-Naphthoquinone (SCHEMBL571061) 0.61 2/20

Clinical trials — most relevant to GAPDH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Interventional Strategy in Tackling Emerging Non-alcoholic Fatty Liver Disease in Childhood Obesity PHASE4COMPLETED
First-line Irinotecan, Lederfolin and 5FU (FOLFIRI) and Bevacizumab in Patients With Advanced Colorectal Cancer PHASE2COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Improving Treatment Outcomes in Chronic Myeloid Leukaemia Patients Using Imatinib and Artesunate Combination Therapy PHASE2ACTIVE_NOT_RECRUITING
Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer PHASE1COMPLETED
The Pathogenesis of Superior Limbic Keratoconjunctivitis nanUNKNOWN
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies nanNOT_YET_RECRUITING
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle nanUNKNOWN
Idarubicin Overcomes MDR1 Induced Chemoresistance With Higher Induction Remission Rate and Quality Than Daunorubicin in Acute Myeloid Leukemia Patients nanUNKNOWN
Metformin Reduce the Relapse Rate on Patients With B-cell Precursor (Ph+ Negative) Acute Lymphoblastic Leukemia nanCOMPLETED
Effect of Branch Chain Amino Acid Therapy on Sarcopenia in Children With Chronic Liver Disease. nanUNKNOWN
Diabetes and Lipid Accumulationand Heart Transplant nanCOMPLETED
Effects of Lead Exposure on Ferroptosis Pathway nanUNKNOWN
Antioxidant Signature in Adult Patients With Phenylketonuria nanCOMPLETED
Prostate Cancer Antigen 3 (PCA-3) Gene Project nanCOMPLETED
Endothelial Colony-Forming Cells in Patients With VWD, AVWS and Healthy Subjects nanRECRUITING
Clinical Trial on Remote Ischemic Conditioning in Acute Ischemic Stroke Within 9 Hours of Onset in Patients Ineligible to Recanalization Therapies nanCOMPLETED
Endometrial Heparin-binding Epidermal Growth Factor Expression nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC nanCOMPLETED
Salivary Biomarkers for Non-small Cell Lung Cancer Detection nanUNKNOWN
The Epigenetic Regulatory Role of P-element Induced Wimpy Testis (Piwi) Interacting RNA-823 (piR-823) in Ovarian Cancer Progression nanUNKNOWN
Ephrin B1 Regulation in Human Right Appendage nanCOMPLETED
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis nanCOMPLETED
Structural Network on Prostate Cancer in the French Greater West Region nanCOMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
The Effects of Chronic Exercise on UCP1 Gene in Human White Adipose Tissue nanCOMPLETED
Control Ovarian Stimulation Timing Test nanUNKNOWN
Association Between PM2.5 and Ferroptosis nanUNKNOWN
Somatosensory Modulation of Salivary Gene Expression and Oral Feeding in Preterm Infants nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GAPDH binder may also engage these)

ProteinNameSimilarity
P48812 1.000 P48812 →
Q12552 1.000 Q12552 →
P28844 1.000 P28844 →
Q6K5G8 1.000 Q6K5G8 →
A3FKF7 1.000 A3FKF7 →
P32810 1.000 P32810 →
P0A9B5 1.000 P0A9B5 →
O13507 1.000 O13507 →
P46406 1.000 P46406 →
P0CN74 1.000 P0CN74 →
P17244 1.000 P17244 →
P10097 1.000 P10097 →
P17878 1.000 P17878 →
P16858 1.000 P16858 →
P00355 1.000 P00355 →
P26520 1.000 P26520 →
Q8NK47 1.000 Q8NK47 →
P34920 1.000 P34920 →
Q5R2J2 1.000 Q5R2J2 →
P08735 1.000 P08735 →
Q01982 1.000 Q01982 →
P04796 1.000 P04796 →
Q00584 1.000 Q00584 →
Q9FX54 1.000 Q9FX54 →
Q9UR38 1.000 Q9UR38 →
Q5RAB4 1.000 Q5RAB4 →
Q9N2D5 1.000 Q9N2D5 →
P32636 1.000 P32636 →
Q7FAH2 1.000 Q7FAH2 →
Q4KYY3 1.000 Q4KYY3 →