Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19590621 | 0.93 | PTGS1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL19590612 | 0.90 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL19590608 | 0.84 | — | — | |
| SCHEMBL15723319 | 0.81 | PTGS1 (0.41) | PTGS1PTGS2 | |
| SCHEMBL15723328 | 0.77 | CYP1A2 (0.32) | PTGS1PTGS2 | |
| SCHEMBL15723285 | 0.72 | PTGS2 (0.47) | PTGS1PTGS2 | |
| SCHEMBL15723292 | 0.69 | PTGS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL15723280 | 0.68 | PTGS1 (0.37) | PTGS1PTGS2 | |
| SCHEMBL15726900 | 0.66 | PTGS2 (0.48) | PTGS1PTGS2 | |
| SCHEMBL15723275 | 0.66 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815851-B2 | Pyrrolo carboxamides as modulators of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases | PHENEX PHARMACEUTICALS AG (DE) | 2017-11-14 | — | — | US | disclosed |